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The miR-155–PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation
A single microRNA (miRNA) can regulate the expression of many genes, though the level of repression imparted on any given target is generally low. How then is the selective pressure for a single miRNA/target interaction maintained across long evolutionary distances? We addressed this problem by disr...
Autores principales: | Lu, Dong, Nakagawa, Rinako, Lazzaro, Sandra, Staudacher, Philipp, Abreu-Goodger, Cei, Henley, Tom, Boiani, Sara, Leyland, Rebecca, Galloway, Alison, Andrews, Simon, Butcher, Geoffrey, Nutt, Stephen L., Turner, Martin, Vigorito, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203942/ https://www.ncbi.nlm.nih.gov/pubmed/25288398 http://dx.doi.org/10.1084/jem.20140338 |
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