The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells

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The cornerstone of humoral immunity is the differentiation of B cells into antibody-secreting plasma cells. This process is tightly controlled by a regulatory gene network centered on the transcriptional repressor B lymphocyte–induced maturation protein 1 (Blimp1). Proliferation of activated B cells...

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Detalles Bibliográficos
Autores principales: Grötsch, Bettina, Brachs, Sebastian, Lang, Christiane, Luther, Julia, Derer, Anja, Schlötzer-Schrehardt, Ursula, Bozec, Aline, Fillatreau, Simon, Berberich, Ingolf, Hobeika, Elias, Reth, Michael, Wagner, Erwin F., Schett, Georg, Mielenz, Dirk, David, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203943/
https://www.ncbi.nlm.nih.gov/pubmed/25288397
http://dx.doi.org/10.1084/jem.20130795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203943/
https://www.ncbi.nlm.nih.gov/pubmed/25288397
http://dx.doi.org/10.1084/jem.20130795

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