Targeted exon sequencing fails to identify rare coding variants with large effect in rheumatoid arthritis

INTRODUCTION: Although it has been suggested that rare coding variants could explain the substantial missing heritability, very few sequencing studies have been performed in rheumatoid arthritis (RA). We aimed to identify novel functional variants with rare to low frequency using targeted exon seque...

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Detalles Bibliográficos
Autores principales: Bang, So-Young, Na, Young-Ji, Kim, Kwangwoo, Joo, Young Bin, Park, Youngho, Lee, Jaemoon, Lee, Sun-Young, Ansari, Adnan A, Jung, Junghee, Rhee, Hwanseok, Lee, Jong-Young, Han, Bok-Ghee, Ahn, Sung-Min, Won, Sungho, Lee, Hye-Soon, Bae, Sang-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203956/
https://www.ncbi.nlm.nih.gov/pubmed/25267259
http://dx.doi.org/10.1186/s13075-014-0447-7

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