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Chemically induced mouse liver tumors are resistant to treatment with atorvastatin

BACKGROUND: Atorvastatin is a potent inhibitor of the mevalonate pathway and widely used as a hypolipidemic drug. Some epidemiological studies and animal experiments indicate that the long-term use of atorvastatin and structurally related drugs might be associated with a reduced risk of developing h...

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Detalles Bibliográficos
Autores principales: Braeuning, Albert, Bucher, Philip, Hofmann, Ute, Buchmann, Albrecht, Schwarz, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203962/
https://www.ncbi.nlm.nih.gov/pubmed/25319454
http://dx.doi.org/10.1186/1471-2407-14-766

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