Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets

BACKGROUND: tRFs, 14 to 32 nt long single-stranded RNA derived from mature or precursor tRNAs, are a recently discovered class of small RNA that have been found to be present in diverse organisms at read counts comparable to miRNAs. Currently, there is a debate about their biogenesis and function. R...

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Detalles Bibliográficos
Autores principales: Kumar, Pankaj, Anaya, Jordan, Mudunuri, Suresh B, Dutta, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203973/
https://www.ncbi.nlm.nih.gov/pubmed/25270025
http://dx.doi.org/10.1186/s12915-014-0078-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203973/
https://www.ncbi.nlm.nih.gov/pubmed/25270025
http://dx.doi.org/10.1186/s12915-014-0078-0

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