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FunSeq2: a framework for prioritizing noncoding regulatory variants in cancer

Identification of noncoding drivers from thousands of somatic alterations in a typical tumor is a difficult and unsolved problem. We report a computational framework, FunSeq2, to annotate and prioritize these mutations. The framework combines an adjustable data context integrating large-scale genomi...

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Detalles Bibliográficos
Autores principales:	Fu, Yao, Liu, Zhu, Lou, Shaoke, Bedford, Jason, Mu, Xinmeng Jasmine, Yip, Kevin Y, Khurana, Ekta, Gerstein, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203974/ https://www.ncbi.nlm.nih.gov/pubmed/25273974 http://dx.doi.org/10.1186/s13059-014-0480-5

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