Cargando…

Efficacy and safety of oral recombinant calcitonin tablets in postmenopausal women with low bone mass and increased fracture risk: a randomized, placebo-controlled trial

SUMMARY: The effect of an investigational oral calcitonin tablet upon bone mineral density (BMD) of the spine was investigated in postmenopausal women with low bone mass and at increased risk of fracture. Compared to placebo, calcitonin tablets increased lumbar spine BMD. This agent may provide an a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Binkley, N., Bone, H., Gilligan, J. P., Krause, D. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer London 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203997/ https://www.ncbi.nlm.nih.gov/pubmed/25027109 http://dx.doi.org/10.1007/s00198-014-2796-0

Ejemplares similares

Does salmon calcitonin cause cancer? A review and meta-analysis
por: Wells, G., et al.
Publicado: (2015)

Oral calcitonin
por: Hamdy, Ronald C, et al.
Publicado: (2012)

Cement or Calcitonin for Coccyx Fractures
por: Foye, Patrick M., et al.
Publicado: (2021)

Effect of Nasal Calcitonin on the Health-Related Quality of Life in Postmenopause Women Affected With Low Bone Density
por: Shohrati, Majid, et al.
Publicado: (2015)

Efficacy and Safety of Blonanserin Oral Tablet in Adolescents with Schizophrenia: A 6-Week, Randomized Placebo-Controlled Study
por: Saito, Takuya, et al.
Publicado: (2022)

In response to: “Cement or Calcitonin for Coccyx Fractures”
por: Akar, Ezgi, et al.
Publicado: (2021)

Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin
por: Karsdal, MA, et al.
Publicado: (2008)

A randomized double-blind placebo-controlled trial to investigate the effects of nasal calcitonin on bone microarchitecture measured by high-resolution peripheral quantitative computerized tomography in postmenopausal women — Study protocol
por: Richert, Laura, et al.
Publicado: (2008)

A Randomized Placebo-Controlled Trial Evaluating the Analgesic Effect of Salmon Calcitonin in Refractory Bone Metastasis Pain
por: Jain, Parmanand N, et al.
Publicado: (2020)

Revisiting Estrogen: Efficacy and Safety for Postmenopausal Bone Health
por: Sacco, Sandra M., et al.
Publicado: (2010)

Efficacy, Safety, and Palatability of RACTAB® Formulation Amlodipine Orally Disintegrating Tablets
por: Fukui-Soubou, Mari, et al.
Publicado: (2012)

PERCUTANEOUS TREATMENT OF ANEURYSMAL BONE CYST WITH CALCITONIN AND METHYLPREDNISOLONE
por: Oliveira, Marcelo Bragança dos Reis, et al.
Publicado: (2018)

Calcitonin and Bone Physiology: In Vitro, In Vivo, and Clinical Investigations
por: Xie, Jingbo, et al.
Publicado: (2020)

The Calcitonin and Glucocorticoids Combination: Mechanistic Insights into Their Class–Effect Synergy in Experimental Arthritis
por: Al-Kashi, Adam, et al.
Publicado: (2013)

Efficacy and Safety of Oral Ibandronate versus Intravenous Zoledronic Acid on Bone Metabolism and Bone Mineral Density in Postmenopausal Japanese Women with Osteoporosis
por: Uehara, Masashi, et al.
Publicado: (2021)

Type 2 Diabetes Mellitus Increases the Risk to Hip Fracture in Postmenopausal Osteoporosis by Deteriorating the Trabecular Bone Microarchitecture and Bone Mass
por: Mohsin, Sahar, et al.
Publicado: (2019)

Study on the Effect of Bushen Zhuanggu Tablet Combined with Conventional Regimen on Bone Mineral Density Improvement, Functional Recovery and Fracture Risk Prevention in Patients with Postmenopausal Osteoporosis
por: Chen, Tianliang, et al.
Publicado: (2023)

Safety and efficacy of tocotrienol supplementation for bone health in postmenopausal women: protocol for a dose–response double-blinded placebo-controlled randomised trial
por: Shen, Chwan-Li, et al.
Publicado: (2016)

The calcitonins : physiology and pharmacology /
por: Azria, M. (Moíse), 1936-
Publicado: (1989)

Efficacy and safety of pharmacologic therapies for prevention of osteoporotic vertebral fractures in postmenopausal women
por: Wei, Fei-Long, et al.
Publicado: (2022)

Calcitonin Related Polypeptide Alpha Mediates Oral Cancer Pain
por: Tu, Nguyen Huu, et al.
Publicado: (2023)

Calcitonin substitution in calcitonin deficiency reduces particle-induced osteolysis
por: Kauther, Max D, et al.
Publicado: (2011)

The Calcitonin/Calcitonin Gene-Related Peptide Family in Invertebrate Deuterostomes
por: Sekiguchi, Toshio
Publicado: (2018)

Chronic treatment of Paget's disease of bone with synthetic human calcitonin.
por: Lang, R., et al.
Publicado: (1981)

The Role of the Calcitonin Peptide Family in Prostate Cancer and Bone Metastasis
por: Warrington, Jessica Isabel, et al.
Publicado: (2017)

Research Progress in Calcitonin Gene-Related Peptide and Bone Repair
por: Wang, Qichang, et al.
Publicado: (2023)

Effect of daily oral minodronate on vertebral fractures in Japanese postmenopausal women with established osteoporosis: a randomized placebo-controlled double-blind study
por: Matsumoto, T., et al.
Publicado: (2008)

ACTIVExtend: 24 Months of Alendronate After 18 Months of Abaloparatide or Placebo for Postmenopausal Osteoporosis
por: Bone, Henry G, et al.
Publicado: (2018)

Orally disintegrating vardenafil tablets for the treatment of erectile dysfunction: efficacy, safety, and patient acceptability
por: Green, Roger, et al.
Publicado: (2011)

Efficacy and Safety of Denosumab in Osteoporosis or Low Bone Mineral Density Postmenopausal Women
por: Chen, Yi, et al.
Publicado: (2021)

Romosozumab in Postmenopausal Korean Women with Osteoporosis: A Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study
por: Baek, Ki-Hyun, et al.
Publicado: (2021)

Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts
por: Keller, Johannes, et al.
Publicado: (2014)

Effects of vaginal administration of conjugated estrogens tablet on sexual function in postmenopausal women with sexual dysfunction: a double-blind, randomized, placebo-controlled trial
por: Bumphenkiatikul, Thanapob, et al.
Publicado: (2020)

Influence of Obesity on Bone Turnover Markers and Fracture Risk in Postmenopausal Women
por: López-Gómez, Juan J., et al.
Publicado: (2022)

Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo
por: Dacquin, Romain, et al.
Publicado: (2004)

Clinical effect of intramuscular calcitonin compared with oral celecoxib in the treatment of knee bone marrow lesions: a retrospective study
por: Zhou, Jiaming, et al.
Publicado: (2020)

Overall Safety of Ospemifene in Postmenopausal Women from Placebo-Controlled Phase 2 and 3 Trials
por: Simon, James A., et al.
Publicado: (2018)

The neuropeptide calcitonin gene-related peptide alpha is essential for bone healing
por: Appelt, Jessika, et al.
Publicado: (2020)

Mice Lacking the Calcitonin Receptor Do Not Display Improved Bone Healing
por: Appelt, Jessika, et al.
Publicado: (2021)

Analgesic effect of nasal salmon calcitonin during the early post-fracture period of the distal radius fracture
por: Karponis, A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hmqr47qigp5fk1dpf0d6pfugak