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Unglycosylated recombinant human glutathione peroxidase 3 mutant from Escherichia coli is active as a monomer

Glutathione peroxidase 3 (GPx3) is a glycosylated member of GPx family and can catalyze the reaction of different types of peroxides with GSH to form their corresponding alcohols in vitro. The active center of GPx3 is selenocysteine (Sec), which is incorporated into proteins by a specific mechanism....

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Detalles Bibliográficos
Autores principales: Song, Jian, Yu, Yang, Xing, Ruiqing, Guo, Xiao, Liu, Dali, Wei, Jingyan, Song, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204031/
https://www.ncbi.nlm.nih.gov/pubmed/25331785
http://dx.doi.org/10.1038/srep06698