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(R,S)-Tetrahydropapaveroline production by stepwise fermentation using engineered Escherichia coli

Tetrahydropapaveroline (THP), a benzylisoquinoline alkaloid (BIA) found in diverse pharmaceutical compounds, is used as a starting material for the production of BIA. THP also has various neurobiological properties but is difficult to synthesize. Therefore, a simple method for THP production is desi...

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Detalles Bibliográficos
Autores principales:	Nakagawa, Akira, Matsuzaki, Chiaki, Matsumura, Eitaro, Koyanagi, Takashi, Katayama, Takane, Yamamoto, Kenji, Sato, Fumihiko, Kumagai, Hidehiko, Minami, Hiromichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204043/ https://www.ncbi.nlm.nih.gov/pubmed/25331563 http://dx.doi.org/10.1038/srep06695

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