Cargando…
Population Based Cohort Study for Pediatric Infectious Diseases Research in Vietnam
A population-based cohort study on pediatric infectious diseases was established at Khanh Hoa Province, central Vietnam in 2006, to determine the etiology and risk factors for severe pediatric infectious diseases (SPID) such as acute respiratory infection (ARI), diarrhea and dengue which are the maj...
Autores principales: | , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Tropical Medicine
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204059/ https://www.ncbi.nlm.nih.gov/pubmed/25425951 http://dx.doi.org/10.2149/tmh.2014-S07 |
_version_ | 1782340491597053952 |
---|---|
author | Yoshida, Lay-Myint Suzuki, Motoi Thiem, Vu Dinh Smith, Wolf Peter Tsuzuki, Ataru Huong, Vu Thi Thu Takahashi, Kensuke Miyakawa, Masami Anh, Nguyen Thi Hien Watanabe, Kiwao Ai, Nguyen Thu Thuy Tho, Le Huu Kilgore, Paul Yoshino, Hiroshi Toizumi, Michiko Yasunami, Michio Moriuchi, Hiroyuki Anh, Dang Duc Ariyoshi, Koya |
author_facet | Yoshida, Lay-Myint Suzuki, Motoi Thiem, Vu Dinh Smith, Wolf Peter Tsuzuki, Ataru Huong, Vu Thi Thu Takahashi, Kensuke Miyakawa, Masami Anh, Nguyen Thi Hien Watanabe, Kiwao Ai, Nguyen Thu Thuy Tho, Le Huu Kilgore, Paul Yoshino, Hiroshi Toizumi, Michiko Yasunami, Michio Moriuchi, Hiroyuki Anh, Dang Duc Ariyoshi, Koya |
author_sort | Yoshida, Lay-Myint |
collection | PubMed |
description | A population-based cohort study on pediatric infectious diseases was established at Khanh Hoa Province, central Vietnam in 2006, to determine the etiology and risk factors for severe pediatric infectious diseases (SPID) such as acute respiratory infection (ARI), diarrhea and dengue which are the major causes of under 5 mortality. A population census survey was conducted in Nha-Trang and Ninh-Hoa to collect demographic, social-behavioral data and disease burden on SPID. The study site covered a population of 353,525 residing in 75,826 households with 24,781 children less than 5 years. Hospital databases from two hospitals covering the region were obtained. Linking the census and hospital databases, we were able to investigate on a variety of SPID such as environmental tobacco smoking exposure and increased risked of pediatric pneumonia hospitalization, population density, water supply and risk of dengue fever and animal livestock and risk of hospitalized diarrhea. To determine incidence, viral etiology and risk factors for pediatric ARI/pneumonia, we setup a population based prospective hospitalized Pediatric ARI surveillance at Khanh Hoa General Hospital, Nha-Trang in February 2007. The study has revealed RSV, rhinovirus and influenza A as major viral pathogens, role of multiple viral infection and its interaction with bacteria in the development of pneumonia. In addition, we are also conducting a birth cohort study to investigate the incidence of congenital infection and its impact on physical-neurological development, and role of host genetic polymorphism on SPID hospitalization in Vietnam. Population mobility, high cost of regular census update and low mortality are the challenges. |
format | Online Article Text |
id | pubmed-4204059 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Japanese Society of Tropical Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-42040592014-11-25 Population Based Cohort Study for Pediatric Infectious Diseases Research in Vietnam Yoshida, Lay-Myint Suzuki, Motoi Thiem, Vu Dinh Smith, Wolf Peter Tsuzuki, Ataru Huong, Vu Thi Thu Takahashi, Kensuke Miyakawa, Masami Anh, Nguyen Thi Hien Watanabe, Kiwao Ai, Nguyen Thu Thuy Tho, Le Huu Kilgore, Paul Yoshino, Hiroshi Toizumi, Michiko Yasunami, Michio Moriuchi, Hiroyuki Anh, Dang Duc Ariyoshi, Koya Trop Med Health Presentation A population-based cohort study on pediatric infectious diseases was established at Khanh Hoa Province, central Vietnam in 2006, to determine the etiology and risk factors for severe pediatric infectious diseases (SPID) such as acute respiratory infection (ARI), diarrhea and dengue which are the major causes of under 5 mortality. A population census survey was conducted in Nha-Trang and Ninh-Hoa to collect demographic, social-behavioral data and disease burden on SPID. The study site covered a population of 353,525 residing in 75,826 households with 24,781 children less than 5 years. Hospital databases from two hospitals covering the region were obtained. Linking the census and hospital databases, we were able to investigate on a variety of SPID such as environmental tobacco smoking exposure and increased risked of pediatric pneumonia hospitalization, population density, water supply and risk of dengue fever and animal livestock and risk of hospitalized diarrhea. To determine incidence, viral etiology and risk factors for pediatric ARI/pneumonia, we setup a population based prospective hospitalized Pediatric ARI surveillance at Khanh Hoa General Hospital, Nha-Trang in February 2007. The study has revealed RSV, rhinovirus and influenza A as major viral pathogens, role of multiple viral infection and its interaction with bacteria in the development of pneumonia. In addition, we are also conducting a birth cohort study to investigate the incidence of congenital infection and its impact on physical-neurological development, and role of host genetic polymorphism on SPID hospitalization in Vietnam. Population mobility, high cost of regular census update and low mortality are the challenges. The Japanese Society of Tropical Medicine 2014-06 2014-05-24 /pmc/articles/PMC4204059/ /pubmed/25425951 http://dx.doi.org/10.2149/tmh.2014-S07 Text en 2014 Japanese Society of Tropical Medicine This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Presentation Yoshida, Lay-Myint Suzuki, Motoi Thiem, Vu Dinh Smith, Wolf Peter Tsuzuki, Ataru Huong, Vu Thi Thu Takahashi, Kensuke Miyakawa, Masami Anh, Nguyen Thi Hien Watanabe, Kiwao Ai, Nguyen Thu Thuy Tho, Le Huu Kilgore, Paul Yoshino, Hiroshi Toizumi, Michiko Yasunami, Michio Moriuchi, Hiroyuki Anh, Dang Duc Ariyoshi, Koya Population Based Cohort Study for Pediatric Infectious Diseases Research in Vietnam |
title | Population Based Cohort Study for Pediatric Infectious Diseases Research in Vietnam |
title_full | Population Based Cohort Study for Pediatric Infectious Diseases Research in Vietnam |
title_fullStr | Population Based Cohort Study for Pediatric Infectious Diseases Research in Vietnam |
title_full_unstemmed | Population Based Cohort Study for Pediatric Infectious Diseases Research in Vietnam |
title_short | Population Based Cohort Study for Pediatric Infectious Diseases Research in Vietnam |
title_sort | population based cohort study for pediatric infectious diseases research in vietnam |
topic | Presentation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204059/ https://www.ncbi.nlm.nih.gov/pubmed/25425951 http://dx.doi.org/10.2149/tmh.2014-S07 |
work_keys_str_mv | AT yoshidalaymyint populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT suzukimotoi populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT thiemvudinh populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT smithwolfpeter populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT tsuzukiataru populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT huongvuthithu populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT takahashikensuke populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT miyakawamasami populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT anhnguyenthihien populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT watanabekiwao populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT ainguyenthuthuy populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT tholehuu populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT kilgorepaul populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT yoshinohiroshi populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT toizumimichiko populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT yasunamimichio populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT moriuchihiroyuki populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT anhdangduc populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam AT ariyoshikoya populationbasedcohortstudyforpediatricinfectiousdiseasesresearchinvietnam |