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Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25

The genetic contributions to breast cancer development among Latinas are not well understood. Here we carry out a genome-wide association study of breast cancer in Latinas and identify a genome-wide significant risk variant, located 5′ of the Estrogen Receptor 1 gene (ESR1; 6q25 region). The minor a...

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Detalles Bibliográficos
Autores principales: Fejerman, Laura, Ahmadiyeh, Nasim, Hu, Donglei, Huntsman, Scott, Beckman, Kenneth B., Caswell, Jennifer L., Tsung, Karen, John, Esther M., Torres-Mejia, Gabriela, Carvajal-Carmona, Luis, Echeverry, María Magdalena, Tuazon, Anna Marie D., Ramirez, Carolina, Gignoux, Christopher R., Eng, Celeste, Gonzalez-Burchard, Esteban, Henderson, Brian, Marchand, Loic Le, Kooperberg, Charles, Hou, Lifang, Agalliu, Ilir, Kraft, Peter, Lindström, Sara, Perez-Stable, Eliseo J., Haiman, Christopher A., Ziv, Elad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204111/
https://www.ncbi.nlm.nih.gov/pubmed/25327703
http://dx.doi.org/10.1038/ncomms6260

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