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The effect of extracorporeal shock wave lithotripsy in the management of idiopathic gallstones in children

OBJECTIVE: The most common etiology for gallstones in children is hemolytic diseases; however, the prevalence of nonhemolytic gallstones, which are mostly idiopathic, is increasing. Several studies concerning the treatment of gallstones with respect to the influence of extracorporeal shock wave lith...

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Autores principales: Mousavi, Seyed Abdollah, Karami, Hasan, Barzegarnejad, Ayub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204247/
https://www.ncbi.nlm.nih.gov/pubmed/25336804
http://dx.doi.org/10.4103/0971-9261.142010
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author Mousavi, Seyed Abdollah
Karami, Hasan
Barzegarnejad, Ayub
author_facet Mousavi, Seyed Abdollah
Karami, Hasan
Barzegarnejad, Ayub
author_sort Mousavi, Seyed Abdollah
collection PubMed
description OBJECTIVE: The most common etiology for gallstones in children is hemolytic diseases; however, the prevalence of nonhemolytic gallstones, which are mostly idiopathic, is increasing. Several studies concerning the treatment of gallstones with respect to the influence of extracorporeal shock wave lithotripsy (ESWL) have been conducted in adults, but not to the same extent in children. Therefore, this study attempted to examine the effects of lithotripsy on idiopathic gallstones in children. MATERIALS AND METHODS: In this study, 12 children, all of whom were under 12 years of age and diagnosed with idiopathic gallstones, were treated with ESWL. The average age of the children examined in this study was 6.5 years (range 3-11 years). Patients were treated with 2500-3000 shockwaves per session. The number of shockwaves was 90 shocks/min and the impulse intensity ranged from 10 to 12 kV. The final goal was the fragmentation of stones in pieces with less than 3 mm in dimension. Patients were followed up for 6-30 months. RESULTS: A total of 12 patients were treated with ESWL for 14 rounds. In three patients, complete fragmentation occurred within the first trial and was cleared. The nine remaining patients underwent ESWL 10 times in which an acceptable change in the gallstone's condition was not observed. Five of the patients underwent surgery. The chemical composition of the gallstones showed that the dominant element in them was calcium. CONCLUSIONS: Our findings show that performing ESWL can be effective in some children. Further studies with larger population are recommended. Furthermore, it seems increasing the voltage intensity and frequency as conducted in adults accompanied with biliary acids prescription can be effective in children.
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spelling pubmed-42042472014-10-21 The effect of extracorporeal shock wave lithotripsy in the management of idiopathic gallstones in children Mousavi, Seyed Abdollah Karami, Hasan Barzegarnejad, Ayub J Indian Assoc Pediatr Surg Original Article OBJECTIVE: The most common etiology for gallstones in children is hemolytic diseases; however, the prevalence of nonhemolytic gallstones, which are mostly idiopathic, is increasing. Several studies concerning the treatment of gallstones with respect to the influence of extracorporeal shock wave lithotripsy (ESWL) have been conducted in adults, but not to the same extent in children. Therefore, this study attempted to examine the effects of lithotripsy on idiopathic gallstones in children. MATERIALS AND METHODS: In this study, 12 children, all of whom were under 12 years of age and diagnosed with idiopathic gallstones, were treated with ESWL. The average age of the children examined in this study was 6.5 years (range 3-11 years). Patients were treated with 2500-3000 shockwaves per session. The number of shockwaves was 90 shocks/min and the impulse intensity ranged from 10 to 12 kV. The final goal was the fragmentation of stones in pieces with less than 3 mm in dimension. Patients were followed up for 6-30 months. RESULTS: A total of 12 patients were treated with ESWL for 14 rounds. In three patients, complete fragmentation occurred within the first trial and was cleared. The nine remaining patients underwent ESWL 10 times in which an acceptable change in the gallstone's condition was not observed. Five of the patients underwent surgery. The chemical composition of the gallstones showed that the dominant element in them was calcium. CONCLUSIONS: Our findings show that performing ESWL can be effective in some children. Further studies with larger population are recommended. Furthermore, it seems increasing the voltage intensity and frequency as conducted in adults accompanied with biliary acids prescription can be effective in children. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4204247/ /pubmed/25336804 http://dx.doi.org/10.4103/0971-9261.142010 Text en Copyright: © Journal of Indian Association of Pediatric Surgeons http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Mousavi, Seyed Abdollah
Karami, Hasan
Barzegarnejad, Ayub
The effect of extracorporeal shock wave lithotripsy in the management of idiopathic gallstones in children
title The effect of extracorporeal shock wave lithotripsy in the management of idiopathic gallstones in children
title_full The effect of extracorporeal shock wave lithotripsy in the management of idiopathic gallstones in children
title_fullStr The effect of extracorporeal shock wave lithotripsy in the management of idiopathic gallstones in children
title_full_unstemmed The effect of extracorporeal shock wave lithotripsy in the management of idiopathic gallstones in children
title_short The effect of extracorporeal shock wave lithotripsy in the management of idiopathic gallstones in children
title_sort effect of extracorporeal shock wave lithotripsy in the management of idiopathic gallstones in children
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204247/
https://www.ncbi.nlm.nih.gov/pubmed/25336804
http://dx.doi.org/10.4103/0971-9261.142010
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