Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia

The FANCJ DNA helicase is mutated in hereditary breast and ovarian cancer as well as the progressive bone marrow failure disorder Fanconi anemia (FA). FANCJ is linked to cancer suppression and DNA double strand break repair through its direct interaction with the hereditary breast cancer associated...

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Detalles Bibliográficos
Autores principales: Brosh, Robert M., Cantor, Sharon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204437/
https://www.ncbi.nlm.nih.gov/pubmed/25374583
http://dx.doi.org/10.3389/fgene.2014.00372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204437/
https://www.ncbi.nlm.nih.gov/pubmed/25374583
http://dx.doi.org/10.3389/fgene.2014.00372

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