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Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia
The FANCJ DNA helicase is mutated in hereditary breast and ovarian cancer as well as the progressive bone marrow failure disorder Fanconi anemia (FA). FANCJ is linked to cancer suppression and DNA double strand break repair through its direct interaction with the hereditary breast cancer associated...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204437/ https://www.ncbi.nlm.nih.gov/pubmed/25374583 http://dx.doi.org/10.3389/fgene.2014.00372 |