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Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance

BACKGROUND: Celiac disease is a common cause of chronic diarrhea and malabsorption syndrome all over the world. Though it was considered uncommon in India in past, it is being described frequently recently. Some patients with celiac disease do not improve despite gluten free diet (GFD). A study desc...

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Autores principales: Ghoshal, Uday C, Ghoshal, Ujjala, Misra, Asha, Choudhuri, Gourdas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420464/
https://www.ncbi.nlm.nih.gov/pubmed/15154971
http://dx.doi.org/10.1186/1471-230X-4-10
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author Ghoshal, Uday C
Ghoshal, Ujjala
Misra, Asha
Choudhuri, Gourdas
author_facet Ghoshal, Uday C
Ghoshal, Ujjala
Misra, Asha
Choudhuri, Gourdas
author_sort Ghoshal, Uday C
collection PubMed
description BACKGROUND: Celiac disease is a common cause of chronic diarrhea and malabsorption syndrome all over the world. Though it was considered uncommon in India in past, it is being described frequently recently. Some patients with celiac disease do not improve despite gluten free diet (GFD). A study described 15 cases of celiac disease unresponsive to GFD in whom small intestinal bacterial overgrowth (SIBO) or lactose intolerance was the cause for unresponsiveness. CASE PRESENTATION: During a three-year period, 12 adult patients with celiac disease were seen in the Luminal Gastroenterology Clinic in a tertiary referral center in northern India. Two of these 12 patients (16.6%), who did not fully respond to GFD initially, are presented here. Unresponsiveness resulted from SIBO in one and lactose intolerance in the other. The former patient responded to antibiotics and the latter to lactose withdrawal in addition to standard GFD. CONCLUSION: In patients with celiac disease partially responsive or unresponsive to GFD, SIBO and lactose intolerance should be suspected; appropriate investigations and treatment for these may result in complete recovery.
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spelling pubmed-4204642004-06-11 Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance Ghoshal, Uday C Ghoshal, Ujjala Misra, Asha Choudhuri, Gourdas BMC Gastroenterol Case Report BACKGROUND: Celiac disease is a common cause of chronic diarrhea and malabsorption syndrome all over the world. Though it was considered uncommon in India in past, it is being described frequently recently. Some patients with celiac disease do not improve despite gluten free diet (GFD). A study described 15 cases of celiac disease unresponsive to GFD in whom small intestinal bacterial overgrowth (SIBO) or lactose intolerance was the cause for unresponsiveness. CASE PRESENTATION: During a three-year period, 12 adult patients with celiac disease were seen in the Luminal Gastroenterology Clinic in a tertiary referral center in northern India. Two of these 12 patients (16.6%), who did not fully respond to GFD initially, are presented here. Unresponsiveness resulted from SIBO in one and lactose intolerance in the other. The former patient responded to antibiotics and the latter to lactose withdrawal in addition to standard GFD. CONCLUSION: In patients with celiac disease partially responsive or unresponsive to GFD, SIBO and lactose intolerance should be suspected; appropriate investigations and treatment for these may result in complete recovery. BioMed Central 2004-05-22 /pmc/articles/PMC420464/ /pubmed/15154971 http://dx.doi.org/10.1186/1471-230X-4-10 Text en Copyright © 2004 Ghoshal et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
spellingShingle Case Report
Ghoshal, Uday C
Ghoshal, Ujjala
Misra, Asha
Choudhuri, Gourdas
Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance
title Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance
title_full Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance
title_fullStr Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance
title_full_unstemmed Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance
title_short Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance
title_sort partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420464/
https://www.ncbi.nlm.nih.gov/pubmed/15154971
http://dx.doi.org/10.1186/1471-230X-4-10
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