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Clinicopathological Characteristics of Colon Cancer Diagnosed at Primary Health Care Institutions
BACKGROUND/AIMS: The purpose of this study was to evaluate the clinicopathologic characteristics of colon cancers detected at the SOK Sokpeynhan Internal Medical Network, a nationwide system of primary health care institutions. METHODS: We analyzed 579 colon cancer patients diagnosed using colonosco...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association for the Study of Intestinal Diseases
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204700/ https://www.ncbi.nlm.nih.gov/pubmed/25349580 http://dx.doi.org/10.5217/ir.2014.12.2.131 |
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author | Park, Sang Hyun Song, Chi Wook Kim, Yun Bae Kim, Young Sun Chun, Hwang Rae Lee, Jung Hyun Seol, Won Jong Yoon, Hyung Sun Lee, Myung Kwon Lee, Jong Hyup Bhang, Choon Sang Park, Jae Hyung Park, Ji Young Do, Byung Hun Park, Young Dae Yoon, Sang Jeong Park, Chan Wook Yoon, Su Mi Choi, Jong Hwan Shin, Ki Chul Ko, Dong Hoon Kim, Young Jin Seol, Dong Choon |
author_facet | Park, Sang Hyun Song, Chi Wook Kim, Yun Bae Kim, Young Sun Chun, Hwang Rae Lee, Jung Hyun Seol, Won Jong Yoon, Hyung Sun Lee, Myung Kwon Lee, Jong Hyup Bhang, Choon Sang Park, Jae Hyung Park, Ji Young Do, Byung Hun Park, Young Dae Yoon, Sang Jeong Park, Chan Wook Yoon, Su Mi Choi, Jong Hwan Shin, Ki Chul Ko, Dong Hoon Kim, Young Jin Seol, Dong Choon |
author_sort | Park, Sang Hyun |
collection | PubMed |
description | BACKGROUND/AIMS: The purpose of this study was to evaluate the clinicopathologic characteristics of colon cancers detected at the SOK Sokpeynhan Internal Medical Network, a nationwide system of primary health care institutions. METHODS: We analyzed 579 colon cancer patients diagnosed using colonoscopy at the SOK network from January 2011 through December 2012. Cancers from the rectum to the splenic flexure were classified as left colon cancer. Patients over 65 were classified as senior. RESULTS: The mean age (±SD) of subjects was 60.9±10.5 years and 61.1% were men. More than one quarter (28.2%) of patients were asymptomatic. The prevalence of left colon cancer was higher (77.9%) than that for right colon cancer. The most frequent macroscopic and histologic types were depressed (58.9%) and moderately differentiated adenocarcinoma (52.2%), respectively. Asymptomatic subjects displayed protruding or well differentiated adenocarcinoma, while symptomatic patients were more likely to display depressed or moderately differentiated adenocarcinoma (P<0.05). The mean age of the right colon cancer group was higher than that for the left colon cancer group (P<0.05). Among symptomatic patients, the most frequent symptoms were bloody stool for patients with left colon cancer and abdominal discomfort for patients with right colon cancer (P<0.05). The prevalence of depressed cancer was higher in older subjects as compared to younger subjects (P<0.05). The prevalence of right colon cancer tended to increase with age, although this difference did not achieve statistical significance (P>0.05). CONCLUSIONS: Study results indicated an increase of colon cancer amongst younger demographics in recent years. The effectiveness of colonoscopy screening was also evident, as asymptomatic patients demonstrated frequent findings of well differentiated adenocarcinomas. Study results also suggested a need for closer examination of older patients, as right colon cancer tended to increase with age. |
format | Online Article Text |
id | pubmed-4204700 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Korean Association for the Study of Intestinal Diseases |
record_format | MEDLINE/PubMed |
spelling | pubmed-42047002014-10-27 Clinicopathological Characteristics of Colon Cancer Diagnosed at Primary Health Care Institutions Park, Sang Hyun Song, Chi Wook Kim, Yun Bae Kim, Young Sun Chun, Hwang Rae Lee, Jung Hyun Seol, Won Jong Yoon, Hyung Sun Lee, Myung Kwon Lee, Jong Hyup Bhang, Choon Sang Park, Jae Hyung Park, Ji Young Do, Byung Hun Park, Young Dae Yoon, Sang Jeong Park, Chan Wook Yoon, Su Mi Choi, Jong Hwan Shin, Ki Chul Ko, Dong Hoon Kim, Young Jin Seol, Dong Choon Intestinal Res Original Article BACKGROUND/AIMS: The purpose of this study was to evaluate the clinicopathologic characteristics of colon cancers detected at the SOK Sokpeynhan Internal Medical Network, a nationwide system of primary health care institutions. METHODS: We analyzed 579 colon cancer patients diagnosed using colonoscopy at the SOK network from January 2011 through December 2012. Cancers from the rectum to the splenic flexure were classified as left colon cancer. Patients over 65 were classified as senior. RESULTS: The mean age (±SD) of subjects was 60.9±10.5 years and 61.1% were men. More than one quarter (28.2%) of patients were asymptomatic. The prevalence of left colon cancer was higher (77.9%) than that for right colon cancer. The most frequent macroscopic and histologic types were depressed (58.9%) and moderately differentiated adenocarcinoma (52.2%), respectively. Asymptomatic subjects displayed protruding or well differentiated adenocarcinoma, while symptomatic patients were more likely to display depressed or moderately differentiated adenocarcinoma (P<0.05). The mean age of the right colon cancer group was higher than that for the left colon cancer group (P<0.05). Among symptomatic patients, the most frequent symptoms were bloody stool for patients with left colon cancer and abdominal discomfort for patients with right colon cancer (P<0.05). The prevalence of depressed cancer was higher in older subjects as compared to younger subjects (P<0.05). The prevalence of right colon cancer tended to increase with age, although this difference did not achieve statistical significance (P>0.05). CONCLUSIONS: Study results indicated an increase of colon cancer amongst younger demographics in recent years. The effectiveness of colonoscopy screening was also evident, as asymptomatic patients demonstrated frequent findings of well differentiated adenocarcinomas. Study results also suggested a need for closer examination of older patients, as right colon cancer tended to increase with age. Korean Association for the Study of Intestinal Diseases 2014-04 2014-04-29 /pmc/articles/PMC4204700/ /pubmed/25349580 http://dx.doi.org/10.5217/ir.2014.12.2.131 Text en © Copyright 2014. Korean Association for the Study of Intestinal Diseases. All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Park, Sang Hyun Song, Chi Wook Kim, Yun Bae Kim, Young Sun Chun, Hwang Rae Lee, Jung Hyun Seol, Won Jong Yoon, Hyung Sun Lee, Myung Kwon Lee, Jong Hyup Bhang, Choon Sang Park, Jae Hyung Park, Ji Young Do, Byung Hun Park, Young Dae Yoon, Sang Jeong Park, Chan Wook Yoon, Su Mi Choi, Jong Hwan Shin, Ki Chul Ko, Dong Hoon Kim, Young Jin Seol, Dong Choon Clinicopathological Characteristics of Colon Cancer Diagnosed at Primary Health Care Institutions |
title | Clinicopathological Characteristics of Colon Cancer Diagnosed at Primary Health Care Institutions |
title_full | Clinicopathological Characteristics of Colon Cancer Diagnosed at Primary Health Care Institutions |
title_fullStr | Clinicopathological Characteristics of Colon Cancer Diagnosed at Primary Health Care Institutions |
title_full_unstemmed | Clinicopathological Characteristics of Colon Cancer Diagnosed at Primary Health Care Institutions |
title_short | Clinicopathological Characteristics of Colon Cancer Diagnosed at Primary Health Care Institutions |
title_sort | clinicopathological characteristics of colon cancer diagnosed at primary health care institutions |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204700/ https://www.ncbi.nlm.nih.gov/pubmed/25349580 http://dx.doi.org/10.5217/ir.2014.12.2.131 |
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