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An In Silico Agent-Based Model Demonstrates Reelin Function in Directing Lamination of Neurons during Cortical Development

The characteristic six-layered appearance of the neocortex arises from the correct positioning of pyramidal neurons during development and alterations in this process can cause intellectual disabilities and developmental delay. Malformations in cortical development arise when neurons either fail to...

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Detalles Bibliográficos
Autores principales: Caffrey, James R., Hughes, Barry D., Britto, Joanne M., Landman, Kerry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204858/
https://www.ncbi.nlm.nih.gov/pubmed/25334023
http://dx.doi.org/10.1371/journal.pone.0110415