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An In Silico Agent-Based Model Demonstrates Reelin Function in Directing Lamination of Neurons during Cortical Development
The characteristic six-layered appearance of the neocortex arises from the correct positioning of pyramidal neurons during development and alterations in this process can cause intellectual disabilities and developmental delay. Malformations in cortical development arise when neurons either fail to...
Autores principales: | Caffrey, James R., Hughes, Barry D., Britto, Joanne M., Landman, Kerry A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204858/ https://www.ncbi.nlm.nih.gov/pubmed/25334023 http://dx.doi.org/10.1371/journal.pone.0110415 |
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