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Role of promoter hypermethylation in Cisplatin treatment response of male germ cell tumors

BACKGROUND: Male germ cell tumor (GCT) is a highly curable malignancy, which exhibits exquisite sensitivity to cisplatin treatment. The genetic pathway(s) that determine the chemotherapy sensitivity in GCT remain largely unknown. RESULTS: We studied epigenetic changes in relation to cisplatin respon...

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Detalles Bibliográficos
Autores principales:	Koul, Sanjay, McKiernan, James M, Narayan, Gopeshwar, Houldsworth, Jane, Bacik, Jennifer, Dobrzynski, Deborah L, Assaad, Adel M, Mansukhani, Mahesh, Reuter, Victor E, Bosl, George J, Chaganti, Raju SK, Murty, Vundavalli VVS
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420487/ https://www.ncbi.nlm.nih.gov/pubmed/15149548 http://dx.doi.org/10.1186/1476-4598-3-16

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