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Marked Cortisol Production by Intracrine ACTH in GIP-Treated Cultured Adrenal Cells in Which the GIP Receptor Was Exogenously Introduced

The ectopic expression of the glucose-dependent insulinotropic polypeptide receptor (GIPR) in the human adrenal gland causes significant hypercortisolemia after ingestion of each meal and leads to Cushing’s syndrome, implying that human GIPR activation is capable of robustly activating adrenal gluco...

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Detalles Bibliográficos
Autores principales:	Fujii, Hiroko, Tamamori-Adachi, Mimi, Uchida, Kousuke, Susa, Takao, Nakakura, Takashi, Hagiwara, Haruo, Iizuka, Masayoshi, Okinaga, Hiroko, Tanaka, Yuji, Okazaki, Tomoki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204891/ https://www.ncbi.nlm.nih.gov/pubmed/25334044 http://dx.doi.org/10.1371/journal.pone.0110543

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