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Genetic Ablation of Afadin Causes Mislocalization and Deformation of Paneth Cells in the Mouse Small Intestinal Epithelium

Afadin is an actin filament-binding protein that acts cooperatively in cell adhesion with the cell adhesion molecule nectin, and in directional cell movement with the small G protein Rap1 in a nectin-independent manner. We studied the role of afadin in the organization of the small intestinal epithe...

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Detalles Bibliográficos
Autores principales: Tanaka-Okamoto, Miki, Itoh, Yu, Miyoshi, Jun, Mizoguchi, Akira, Mizutani, Kiyohito, Takai, Yoshimi, Inoue, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204899/
https://www.ncbi.nlm.nih.gov/pubmed/25333284
http://dx.doi.org/10.1371/journal.pone.0110549

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