Cargando…
Genetic Ablation of Afadin Causes Mislocalization and Deformation of Paneth Cells in the Mouse Small Intestinal Epithelium
Afadin is an actin filament-binding protein that acts cooperatively in cell adhesion with the cell adhesion molecule nectin, and in directional cell movement with the small G protein Rap1 in a nectin-independent manner. We studied the role of afadin in the organization of the small intestinal epithe...
Autores principales: | Tanaka-Okamoto, Miki, Itoh, Yu, Miyoshi, Jun, Mizoguchi, Akira, Mizutani, Kiyohito, Takai, Yoshimi, Inoue, Masahiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204899/ https://www.ncbi.nlm.nih.gov/pubmed/25333284 http://dx.doi.org/10.1371/journal.pone.0110549 |
Ejemplares similares
-
Involvement of afadin in barrier function and homeostasis of mouse intestinal epithelia
por: Tanaka-Okamoto, Miki, et al.
Publicado: (2011) -
Afadin regulates actomyosin organization through αE-catenin at adherens junctions
por: Sakakibara, Shotaro, et al.
Publicado: (2020) -
Genetic Deletion of Afadin Causes Hydrocephalus by Destruction of Adherens Junctions in Radial Glial and Ependymal Cells in the Midbrain
por: Yamamoto, Hideaki, et al.
Publicado: (2013) -
Afadin: A Key Molecule Essential for Structural Organization of Cell–Cell Junctions of Polarized Epithelia during Embryogenesis
por: Ikeda, Wataru, et al.
Publicado: (1999) -
Afadin Regulates Puncta Adherentia Junction Formation and Presynaptic Differentiation in Hippocampal Neurons
por: Toyoshima, Daisaku, et al.
Publicado: (2014)