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Whole cells in enantioselective reduction of benzyl acetoacetate
The β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium al...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Sociedade Brasileira de Microbiologia
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204978/ https://www.ncbi.nlm.nih.gov/pubmed/25477927 |
| _version_ | 1782340637687808000 |
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| author | Ribeiro, Joyce Benzaquem Ramos, Aline de Souza Lopes, Raquel de Oliveira da Silva, Gabriela Veloso Vieira de Souza, Rodrigo Octavio Mendonça Alves |
| author_facet | Ribeiro, Joyce Benzaquem Ramos, Aline de Souza Lopes, Raquel de Oliveira da Silva, Gabriela Veloso Vieira de Souza, Rodrigo Octavio Mendonça Alves |
| author_sort | Ribeiro, Joyce Benzaquem |
| collection | PubMed |
| description | The β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction. |
| format | Online Article Text |
| id | pubmed-4204978 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | Sociedade Brasileira de Microbiologia |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-42049782014-12-04 Whole cells in enantioselective reduction of benzyl acetoacetate Ribeiro, Joyce Benzaquem Ramos, Aline de Souza Lopes, Raquel de Oliveira da Silva, Gabriela Veloso Vieira de Souza, Rodrigo Octavio Mendonça Alves Braz J Microbiol Short Communication The β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction. Sociedade Brasileira de Microbiologia 2014-10-09 /pmc/articles/PMC4204978/ /pubmed/25477927 Text en Copyright © 2014, Sociedade Brasileira de Microbiologia All the content of the journal, except where otherwise noted, is licensed under a Creative Commons License CC BY-NC. |
| spellingShingle | Short Communication Ribeiro, Joyce Benzaquem Ramos, Aline de Souza Lopes, Raquel de Oliveira da Silva, Gabriela Veloso Vieira de Souza, Rodrigo Octavio Mendonça Alves Whole cells in enantioselective reduction of benzyl acetoacetate |
| title | Whole cells in enantioselective reduction of benzyl acetoacetate |
| title_full | Whole cells in enantioselective reduction of benzyl acetoacetate |
| title_fullStr | Whole cells in enantioselective reduction of benzyl acetoacetate |
| title_full_unstemmed | Whole cells in enantioselective reduction of benzyl acetoacetate |
| title_short | Whole cells in enantioselective reduction of benzyl acetoacetate |
| title_sort | whole cells in enantioselective reduction of benzyl acetoacetate |
| topic | Short Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204978/ https://www.ncbi.nlm.nih.gov/pubmed/25477927 |
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