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Protein–Polymer Conjugation via Ligand Affinity and Photoactivation of Glutathione S-Transferase

[Image: see text] A photoactivated, site-selective conjugation of poly(ethylene glycol) (PEG) to the glutathione (GSH) binding pocket of glutathione S-transferase (GST) is described. To achieve this, a GSH analogue (GSH-BP) was designed and chemically synthesized with three functionalities: (1) the...

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Detalles Bibliográficos
Autores principales:	Lin, En-Wei, Boehnke, Natalie, Maynard, Heather D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205000/ https://www.ncbi.nlm.nih.gov/pubmed/25315970 http://dx.doi.org/10.1021/bc500380r

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