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Oxidized Low-Density Lipoprotein Suppresses Expression of Prostaglandin E Receptor Subtype EP3 in Human THP-1 Macrophages

EP3, one of four prostaglandin E2 (PGE2) receptors, is significantly lower in atherosclerotic plaques than in normal arteries and is localized predominantly in macrophages of the plaque shoulder region. However, mechanisms behind this EP3 expression pattern are still unknown. We investigated the und...

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Detalles Bibliográficos
Autores principales: Sui, Xuxia, Liu, Yanmin, Li, Qi, Liu, Gefei, Song, Xuhong, Su, Zhongjing, Chang, Xiaolan, Zhou, Yingbi, Liang, Bin, Huang, Dongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205008/
https://www.ncbi.nlm.nih.gov/pubmed/25333975
http://dx.doi.org/10.1371/journal.pone.0110828