Cargando…
Lack of XBP-1 Impedes Murine Cytomegalovirus Gene Expression
The unfolded protein response (UPR) is an endoplasmic reticulum (ER)-to-nucleus signaling cascade induced in response to ER stress. The UPR aims at restoring homeostasis, but can also induce apoptosis if stress persists. Infection by human and murine cytomegaloviruses (CMVs) provokes ER stress and i...
Autores principales: | Drori, Adi, Messerle, Martin, Brune, Wolfram, Tirosh, Boaz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205010/ https://www.ncbi.nlm.nih.gov/pubmed/25333725 http://dx.doi.org/10.1371/journal.pone.0110942 |
Ejemplares similares
-
Repression of viral gene expression and replication by the unfolded protein response effector XBP1u
por: Hinte, Florian, et al.
Publicado: (2020) -
Laboratory diagnostics of murine blood for detection of mouse cytomegalovirus (MCMV)-induced hepatitis
por: Stahl, Felix R., et al.
Publicado: (2018) -
Cytomegalovirus Downregulates IRE1 to Repress the Unfolded Protein Response
por: Stahl, Sebastian, et al.
Publicado: (2013) -
XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells
por: Tirosh, Boaz, et al.
Publicado: (2005) -
Prevention of Cellular Suicide by Cytomegaloviruses
por: Fliss, Patricia M., et al.
Publicado: (2012)