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Development of Synthetic Lethality Anticancer Therapeutics: Miniperspective
[Image: see text] The concept of synthetic lethality (the creation of a lethal phenotype from the combined effects of mutations in two or more genes) has recently been exploited in various efforts to develop new genotype-selective anticancer therapeutics. These efforts include screening for novel an...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205018/ https://www.ncbi.nlm.nih.gov/pubmed/24893124 http://dx.doi.org/10.1021/jm500415t |