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Orthotopic models of pediatric brain tumors in zebrafish

High-throughput screens (HTS) of compound toxicity against cancer cells can identify thousands of potential new drug-leads. But only limited numbers of these compounds can progress to expensive and labor intensive efficacy studies in mice, creating a ‘bottle-neck’ in the drug development pipeline. A...

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Detalles Bibliográficos
Autores principales: Eden, Christopher J., Ju, Bensheng, Murugesan, Mohankumar, Phoenix, Timothy, Nimmervoll, Birgit, Tong, Yiai, Ellison, David W., Finkelstein, David, Wright, Karen, Boulos, Nidal, Dapper, Jason, Thiruvenkatam, Radhika, Lessman, Charles, Taylor, Michael R., Gilbertson, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205223/
https://www.ncbi.nlm.nih.gov/pubmed/24747973
http://dx.doi.org/10.1038/onc.2014.107

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