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Orthotopic models of pediatric brain tumors in zebrafish
High-throughput screens (HTS) of compound toxicity against cancer cells can identify thousands of potential new drug-leads. But only limited numbers of these compounds can progress to expensive and labor intensive efficacy studies in mice, creating a ‘bottle-neck’ in the drug development pipeline. A...
Autores principales: | Eden, Christopher J., Ju, Bensheng, Murugesan, Mohankumar, Phoenix, Timothy, Nimmervoll, Birgit, Tong, Yiai, Ellison, David W., Finkelstein, David, Wright, Karen, Boulos, Nidal, Dapper, Jason, Thiruvenkatam, Radhika, Lessman, Charles, Taylor, Michael R., Gilbertson, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205223/ https://www.ncbi.nlm.nih.gov/pubmed/24747973 http://dx.doi.org/10.1038/onc.2014.107 |
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