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Continuous requirement for the T cell receptor for regulatory T cell function

Foxp3(+) regulatory T cells (T(reg) cells) maintain immunological tolerance and their deficiency results in fatal multi-organ autoimmunity. Although heightened T cell receptor (TCR) signaling is critical for the differentiation of T(reg) cells, the role of TCR signaling in T(reg) cell function remai...

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Detalles Bibliográficos
Autores principales:	Levine, Andrew G, Arvey, Aaron, Jin, Wei, Rudensky, Alexander Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205268/ https://www.ncbi.nlm.nih.gov/pubmed/25263123 http://dx.doi.org/10.1038/ni.3004

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