Impaired T cell survival promotes mucosal inflammatory disease in SHIP1-deficient mice

T cells play a critical role in immune surveillance at mucosal surfaces. SHIP1(−/−) mice succumb to mucosal inflammatory disease that afflicts the lung and small intestine. The basis of this condition has not been defined. Here we show that SHIP1 is required for the normal persistence and survival o...

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Detalles Bibliográficos
Autores principales: Park, M.Y., Srivastava, N., Sudan, R., Viernes, D.R., Chisholm, J.D., Engelman, R.W., Kerr, W.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205272/
https://www.ncbi.nlm.nih.gov/pubmed/24781051
http://dx.doi.org/10.1038/mi.2014.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205272/
https://www.ncbi.nlm.nih.gov/pubmed/24781051
http://dx.doi.org/10.1038/mi.2014.32

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