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Triptolide inhibits human immunodeficiency virus type 1 replication by promoting proteasomal degradation of Tat protein
BACKGROUND: Plants remain an important source of new drugs, new leads and new chemical entities. Triptolide is a diterpenoid epoxide isolated from Tripterygium wilfordii Hook F that possesses a broad range of bioactivities, including anti-inflammatory, immunosuppressive and anti-tumor properties. Th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205289/ https://www.ncbi.nlm.nih.gov/pubmed/25323821 http://dx.doi.org/10.1186/s12977-014-0088-6 |