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Triptolide inhibits human immunodeficiency virus type 1 replication by promoting proteasomal degradation of Tat protein

BACKGROUND: Plants remain an important source of new drugs, new leads and new chemical entities. Triptolide is a diterpenoid epoxide isolated from Tripterygium wilfordii Hook F that possesses a broad range of bioactivities, including anti-inflammatory, immunosuppressive and anti-tumor properties. Th...

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Detalles Bibliográficos
Autores principales: Wan, Zhitao, Chen, Xulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205289/
https://www.ncbi.nlm.nih.gov/pubmed/25323821
http://dx.doi.org/10.1186/s12977-014-0088-6

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