Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment

Signal transduction by receptor tyrosine kinases (RTKs) and nuclear receptors for steroid hormones is essential for body homeostasis, but the cross-talk between these receptor families is poorly understood. We observed that glucocorticoids inhibit signalling downstream of EGFR, an RTK. The underlyin...

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Detalles Bibliográficos
Autores principales: Lauriola, Mattia, Enuka, Yehoshua, Zeisel, Amit, D’Uva, Gabriele, Roth, Lee, Sharon-Sevilla, Michal, Lindzen, Moshit, Sharma, Kirti, Nevo, Nava, Feldman, Morris, Carvalho, Silvia, Cohen-Dvashi, Hadas, Kedmi, Merav, Ben-Chetrit, Nir, Chen, Alon, Solmi, Rossella, Wiemann, Stefan, Schmitt, Fernando, Domany, Eytan, Yarden, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205848/
https://www.ncbi.nlm.nih.gov/pubmed/25278152
http://dx.doi.org/10.1038/ncomms6073

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