ABRO1 suppresses tumourigenesis and regulates the DNA damage response by stabilizing p53

Abraxas brother 1 (ABRO1) has been reported to be a component of the BRISC complex, a multiprotein complex that specifically cleaves ‘Lys-63’-linked ubiquitin. However, current knowledge of the functions of ABRO1 is limited. Here we report that ABRO1 is frequently downregulated in human liver, kidne...

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Detalles Bibliográficos
Autores principales: Zhang, Jianhong, Cao, Mengmeng, Dong, Jiahong, Li, Changyan, Xu, Wangxiang, Zhan, Yiqun, Wang, Xiaohui, Yu, Miao, Ge, Changhui, Ge, Zhiqiang, Yang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205886/
https://www.ncbi.nlm.nih.gov/pubmed/25283148
http://dx.doi.org/10.1038/ncomms6059

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