Dax1 and Nanog act in parallel to stabilize mouse embryonic stem cells and induced pluripotency

Nanog expression is heterogeneous and dynamic in embryonic stem cells (ESCs). However, the mechanism for stabilizing pluripotency during the transitions between Nanog(high) and Nanog(low) states is not well understood. Here we report that Dax1 acts in parallel with Nanog to regulate mouse ESC (mESCs...

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Detalles Bibliográficos
Autores principales: Zhang, Junlei, Liu, Gaoke, Ruan, Yan, Wang, Jiali, Zhao, Ke, Wan, Ying, Liu, Bing, Zheng, Hongting, Peng, Tao, Wu, Wei, He, Ping, Hu, Fu-Quan, Jian, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205889/
https://www.ncbi.nlm.nih.gov/pubmed/25284313
http://dx.doi.org/10.1038/ncomms6042

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