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A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum

The model pathogen Parastagonospora nodorum is a necrotroph and the causal agent of the wheat disease Septoria nodorum blotch (SNB). The sequenced P. nodorum genome has revealed that the fungus harbours a large number of secondary metabolite genes. Secondary metabolites are known to play important r...

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Autores principales: Chooi, Yit-Heng, Muria-Gonzalez, Mariano Jordi, Solomon, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205913/
https://www.ncbi.nlm.nih.gov/pubmed/25379341
http://dx.doi.org/10.1080/21501203.2014.928386
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author Chooi, Yit-Heng
Muria-Gonzalez, Mariano Jordi
Solomon, Peter S.
author_facet Chooi, Yit-Heng
Muria-Gonzalez, Mariano Jordi
Solomon, Peter S.
author_sort Chooi, Yit-Heng
collection PubMed
description The model pathogen Parastagonospora nodorum is a necrotroph and the causal agent of the wheat disease Septoria nodorum blotch (SNB). The sequenced P. nodorum genome has revealed that the fungus harbours a large number of secondary metabolite genes. Secondary metabolites are known to play important roles in the virulence of plant pathogens, but limited knowledge is available about the SM repertoire of this wheat pathogen. Here, we review the secondary metabolites that have been isolated from P. nodorum and related species of the same genus and provide an in-depth genome-wide overview of the secondary metabolite gene clusters encoded in the P. nodorum genome. The secondary metabolite gene survey reveals that P. nodorum is capable of producing a diverse range of small molecules and exciting prospects exist for discovery of novel virulence factors and bioactive molecules.
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spelling pubmed-42059132014-11-04 A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum Chooi, Yit-Heng Muria-Gonzalez, Mariano Jordi Solomon, Peter S. Mycology Invited Articles The model pathogen Parastagonospora nodorum is a necrotroph and the causal agent of the wheat disease Septoria nodorum blotch (SNB). The sequenced P. nodorum genome has revealed that the fungus harbours a large number of secondary metabolite genes. Secondary metabolites are known to play important roles in the virulence of plant pathogens, but limited knowledge is available about the SM repertoire of this wheat pathogen. Here, we review the secondary metabolites that have been isolated from P. nodorum and related species of the same genus and provide an in-depth genome-wide overview of the secondary metabolite gene clusters encoded in the P. nodorum genome. The secondary metabolite gene survey reveals that P. nodorum is capable of producing a diverse range of small molecules and exciting prospects exist for discovery of novel virulence factors and bioactive molecules. Taylor & Francis 2014-07-03 2014-06-24 /pmc/articles/PMC4205913/ /pubmed/25379341 http://dx.doi.org/10.1080/21501203.2014.928386 Text en © 2014 The Author(s). Published by Taylor & Francis. http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Invited Articles
Chooi, Yit-Heng
Muria-Gonzalez, Mariano Jordi
Solomon, Peter S.
A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum
title A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum
title_full A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum
title_fullStr A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum
title_full_unstemmed A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum
title_short A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum
title_sort genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen parastagonospora nodorum
topic Invited Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205913/
https://www.ncbi.nlm.nih.gov/pubmed/25379341
http://dx.doi.org/10.1080/21501203.2014.928386
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