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Depression in small-vessel disease relates to white matter ultrastructural damage, not disability

OBJECTIVE: To determine whether cerebral small-vessel disease (SVD) is a specific risk factor for depression, whether any association is mediated via white matter damage, and to study the role of depressive symptoms and disability on quality of life (QoL) in this patient group. METHODS: Using path a...

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Detalles Bibliográficos
Autores principales: Brookes, Rebecca L., Herbert, Vanessa, Lawrence, Andrew J., Morris, Robin G., Markus, Hugh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206159/
https://www.ncbi.nlm.nih.gov/pubmed/25230999
http://dx.doi.org/10.1212/WNL.0000000000000882