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Compensatory Motor Neuron Response to Chromatolysis in the Murine hSOD1(G93A) Model of Amyotrophic Lateral Sclerosis

We investigated neuronal self-defense mechanisms in a murine model of amyotrophic lateral sclerosis (ALS), the transgenic hSOD1(G93A), during both the asymptomatic and symptomatic stages. This is an experimental model of endoplasmic reticulum (ER) stress with severe chromatolysis. As a compensatory...

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Detalles Bibliográficos
Autores principales:	Riancho, Javier, Ruiz-Soto, Maria, Villagrá, Nuria T., Berciano, Jose, Berciano, Maria T., Lafarga, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206191/ https://www.ncbi.nlm.nih.gov/pubmed/25374511 http://dx.doi.org/10.3389/fncel.2014.00346

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