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Potent tumor targeting drug release system comprising MMP-2 specific peptide fragment with self-assembling characteristics
Self-assembling peptides are capable of forming a complex containing a cavity where cytotoxic agents can be wrapped in a self-assembling manner. These complexes are beneficial for improving the pharmacological properties and pharmacokinetics of cytotoxic agents, such as doxorubicin and paclitaxel. I...
Autores principales: | Hua, Dan, Kong, Weiling, Zheng, Xuemin, Zhou, Zhixing, Yu, Bing, Li, Yazhou, Wang, Yuli, Yang, Xue, Liu, Changxiao, Tang, Lida, Li, Ying, Gong, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206202/ https://www.ncbi.nlm.nih.gov/pubmed/25342883 http://dx.doi.org/10.2147/DDDT.S67305 |
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