Reassessment of the Role of TSC, mTORC1 and MicroRNAs in Amino Acids-Meditated Translational Control of TOP mRNAs

TOP mRNAs encode components of the translational apparatus, and repression of their translation comprises one mechanism, by which cells encountering amino acid deprivation downregulate the biosynthesis of the protein synthesis machinery. This mode of regulation involves TSC as knockout of TSC1 or TS...

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Detalles Bibliográficos
Autores principales: Patursky-Polischuk, Ilona, Kasir, Judith, Miloslavski, Rachel, Hayouka, Zvi, Hausner-Hanochi, Mirit, Stolovich-Rain, Miri, Tsukerman, Pinchas, Biton, Moshe, Mudhasani, Rajini, Jones, Stephen N., Meyuhas, Oded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206288/
https://www.ncbi.nlm.nih.gov/pubmed/25338081
http://dx.doi.org/10.1371/journal.pone.0109410

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