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Neurotrophic Requirements of Human Motor Neurons Defined Using Amplified and Purified Stem Cell-Derived Cultures
Human motor neurons derived from embryonic and induced pluripotent stem cells (hESCs and hiPSCs) are a potentially important tool for studying motor neuron survival and pathological cell death. However, their basic survival requirements remain poorly characterized. Here, we sought to optimize a robu...
Autores principales: | Lamas, Nuno Jorge, Johnson-Kerner, Bethany, Roybon, Laurent, Kim, Yoon A., Garcia-Diaz, Alejandro, Wichterle, Hynek, Henderson, Christopher E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206291/ https://www.ncbi.nlm.nih.gov/pubmed/25337699 http://dx.doi.org/10.1371/journal.pone.0110324 |
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