Investigation of Cross-Species Translatability of Pharmacological MRI in Awake Nonhuman Primate - A Buprenorphine Challenge Study

BACKGROUND: Pharmacological MRI (phMRI) is a neuroimaging technique where drug-induced hemodynamic responses can represent a pharmacodynamic biomarker to delineate underlying biological consequences of drug actions. In most preclinical studies, animals are anesthetized during image acquisition to mi...

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Detalles Bibliográficos
Autores principales: Seah, Stephanie, Asad, Abu Bakar Ali, Baumgartner, Richard, Feng, Dai, Williams, Donald S., Manigbas, Elaine, Beaver, John D., Reese, Torsten, Henry, Brian, Evelhoch, Jeffrey L., Chin, Chih-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206294/
https://www.ncbi.nlm.nih.gov/pubmed/25337714
http://dx.doi.org/10.1371/journal.pone.0110432

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