Cargando…
Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery
BACKGROUND: Traumatic events during early infancy might damage infants’ psychobiological functioning, such as sleep and cortisol secretion. Infants born with orofacial clefts (OFCs) undergo functional, anatomical, and aesthetic surgery. The aim of the present study was to determine whether infants w...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206390/ https://www.ncbi.nlm.nih.gov/pubmed/25342905 http://dx.doi.org/10.2147/NDT.S71785 |
_version_ | 1782340815030321152 |
---|---|
author | Mueller, Andreas A Kalak, Nadeem Schwenzer-Zimmerer, Katja Holsboer-Trachsler, Edith Brand, Serge |
author_facet | Mueller, Andreas A Kalak, Nadeem Schwenzer-Zimmerer, Katja Holsboer-Trachsler, Edith Brand, Serge |
author_sort | Mueller, Andreas A |
collection | PubMed |
description | BACKGROUND: Traumatic events during early infancy might damage infants’ psychobiological functioning, such as sleep and cortisol secretion. Infants born with orofacial clefts (OFCs) undergo functional, anatomical, and aesthetic surgery. The aim of the present study was to determine whether infants with OFC and undergoing OFC surgery show deteriorated sleep and cortisol secretion compared with healthy controls and with their presurgery status. METHODS: A total of 27 infants with OFC (mean age: 22 weeks) and 30 healthy controls (mean age: 23 weeks) took part in the study. For infants with OFC, sleep actigraphy was performed and saliva cortisol was analyzed 5 days before, during, and 5 days after surgery. For controls, sleep and saliva cortisol were assessed similarly, except for the period taken up with surgery. RESULTS: Compared with healthy controls, infants with OFC undergoing OFC surgery did not differ in sleep and cortisol secretion. Their sleep and cortisol secretion did deteriorate during the perisurgical period but recovered 5 days postsurgery. CONCLUSION: In infants with OFC undergoing corrective surgery, the pattern of results for sleep and cortisol suggests that OFC surgery does not seem to constitute a traumatic event with long-term consequences. |
format | Online Article Text |
id | pubmed-4206390 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-42063902014-10-23 Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery Mueller, Andreas A Kalak, Nadeem Schwenzer-Zimmerer, Katja Holsboer-Trachsler, Edith Brand, Serge Neuropsychiatr Dis Treat Original Research BACKGROUND: Traumatic events during early infancy might damage infants’ psychobiological functioning, such as sleep and cortisol secretion. Infants born with orofacial clefts (OFCs) undergo functional, anatomical, and aesthetic surgery. The aim of the present study was to determine whether infants with OFC and undergoing OFC surgery show deteriorated sleep and cortisol secretion compared with healthy controls and with their presurgery status. METHODS: A total of 27 infants with OFC (mean age: 22 weeks) and 30 healthy controls (mean age: 23 weeks) took part in the study. For infants with OFC, sleep actigraphy was performed and saliva cortisol was analyzed 5 days before, during, and 5 days after surgery. For controls, sleep and saliva cortisol were assessed similarly, except for the period taken up with surgery. RESULTS: Compared with healthy controls, infants with OFC undergoing OFC surgery did not differ in sleep and cortisol secretion. Their sleep and cortisol secretion did deteriorate during the perisurgical period but recovered 5 days postsurgery. CONCLUSION: In infants with OFC undergoing corrective surgery, the pattern of results for sleep and cortisol suggests that OFC surgery does not seem to constitute a traumatic event with long-term consequences. Dove Medical Press 2014-10-15 /pmc/articles/PMC4206390/ /pubmed/25342905 http://dx.doi.org/10.2147/NDT.S71785 Text en © 2014 Mueller et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Mueller, Andreas A Kalak, Nadeem Schwenzer-Zimmerer, Katja Holsboer-Trachsler, Edith Brand, Serge Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery |
title | Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery |
title_full | Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery |
title_fullStr | Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery |
title_full_unstemmed | Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery |
title_short | Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery |
title_sort | cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206390/ https://www.ncbi.nlm.nih.gov/pubmed/25342905 http://dx.doi.org/10.2147/NDT.S71785 |
work_keys_str_mv | AT muellerandreasa cortisollevelsandsleeppatternsininfantswithorofacialcleftsundergoingsurgery AT kalaknadeem cortisollevelsandsleeppatternsininfantswithorofacialcleftsundergoingsurgery AT schwenzerzimmererkatja cortisollevelsandsleeppatternsininfantswithorofacialcleftsundergoingsurgery AT holsboertrachsleredith cortisollevelsandsleeppatternsininfantswithorofacialcleftsundergoingsurgery AT brandserge cortisollevelsandsleeppatternsininfantswithorofacialcleftsundergoingsurgery |