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Tim-3 Negatively Mediates Natural Killer Cell Function in LPS-Induced Endotoxic Shock

Sepsis is an exaggerated inflammatory condition response to different microorganisms with high mortality rates and extremely poor prognosis. Natural killer (NK) cells have been reported to be the major producers of IFN-γ and key players in promoting systematic inflammation in lipopolysaccharide (LPS...

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Detalles Bibliográficos
Autores principales: Hou, Hongyan, Liu, Weiyong, Wu, Shiji, Lu, Yanjun, Peng, Jing, Zhu, Yaowu, Lu, Yanfang, Wang, Feng, Sun, Ziyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206431/
https://www.ncbi.nlm.nih.gov/pubmed/25337993
http://dx.doi.org/10.1371/journal.pone.0110585