Cargando…
Presynaptic Localization of Smn and hnRNP R in Axon Terminals of Embryonic and Postnatal Mouse Motoneurons
Spinal muscular atrophy (SMA) is caused by deficiency of the ubiquitously expressed survival motoneuron (SMN) protein. SMN is crucial component of a complex for the assembly of spliceosomal small nuclear ribonucleoprotein (snRNP) particles. Other cellular functions of SMN are less characterized so f...
Autores principales: | Dombert, Benjamin, Sivadasan, Rajeeve, Simon, Christian M., Jablonka, Sibylle, Sendtner, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206449/ https://www.ncbi.nlm.nih.gov/pubmed/25338097 http://dx.doi.org/10.1371/journal.pone.0110846 |
Ejemplares similares
-
Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin
por: Ghanawi, Hanaa, et al.
Publicado: (2021) -
hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons
por: Briese, Michael, et al.
Publicado: (2018) -
Differential roles of α-, β-, and γ-actin in axon growth and collateral branch formation in motoneurons
por: Moradi, Mehri, et al.
Publicado: (2017) -
Paralogs hnRNP L and hnRNP LL Exhibit Overlapping but Distinct RNA Binding Constraints
por: Smith, Sarah A., et al.
Publicado: (2013) -
Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function
por: Briese, Michael, et al.
Publicado: (2020)