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Silencing of EEF2K (eukaryotic elongation factor-2 kinase) reveals AMPK-ULK1-dependent autophagy in colon cancer cells

EEF2K (eukaryotic elongation factor-2 kinase), also known as Ca(2+)/calmodulin-dependent protein kinase III, functions in downregulating peptide chain elongation through inactivation of EEF2 (eukaryotic translation elongation factor 2). Currently, there is a limited amount of information on the prom...

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Detalles Bibliográficos
Autores principales: Xie, Chuan-Ming, Liu, Xiao-Yu, Sham, Kathy WY, Lai, Josie MY, Cheng, Christopher HK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206530/
https://www.ncbi.nlm.nih.gov/pubmed/24955726
http://dx.doi.org/10.4161/auto.29164