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Parthenolide inhibits osteoclast differentiation and bone resorbing activity by down-regulation of NFATc1 induction and c-Fos stability, during RANKL-mediated osteoclastogenesis

Parthenolide, a natural product derived from Feverfew, prevents septic shock and inflammation. We aimed to identify the effects of parthenolide on the RANKL (receptor activator of NF-κB ligand)-induced differentiation and bone resorbing activity of osteoclasts. In this study, parthenolide dose-depen...

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Detalles Bibliográficos
Autores principales:	Kim, Ju-Young, Cheon, Yoon-Hee, Yoon, Kwon-Ha, Lee, Myeung Su, Oh, Jaemin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206717/ https://www.ncbi.nlm.nih.gov/pubmed/24314143 http://dx.doi.org/10.5483/BMBRep.2014.47.8.206

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