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GATA4 negatively regulates osteoblast differentiation by downregulation of Runx2

Osteoblasts are specialized mesenchymal cells that are responsible for bone formation. In this study, we examine the role of GATA4 in osteoblast differentiation. GATA4 was abundantly expressed in preosteoblast cells and gradually down-regulated during osteoblast differentiation. Overexpression of GA...

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Detalles Bibliográficos
Autores principales: Song, Insun, Kim, Kabsun, Kim, Jung Ha, Lee, Young-Kyoung, Jung, Hyun-Jung, Byun, Hae-Ok, Yoon, Gyesoon, Kim, Nacksung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206719/
https://www.ncbi.nlm.nih.gov/pubmed/24355298
http://dx.doi.org/10.5483/BMBRep.2014.47.8.225

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