Characterization of EBV-related Lymphoproliferative Lesions Arising in Donor Lymphocytes of Transplanted Human Tumor Tissues in the NOG Mouse

Human tumor tissue line models established in the severely immunodeficient NOD.Cg-Prkdc(scid) Il2rg(tm1Sug)/Jic (NOD/Shi-scid, IL-2Rγ(null) or NOG) mouse are important tools for oncology research. During the establishment process, a lymphoproliferative lesion (LPL) that replaces the original tumor c...

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Detalles Bibliográficos
Autores principales: Fujii, Etsuko, Kato, Atsuhiko, Chen, Yu Jau, Matsubara, Koichi, Ohnishi, Yasuyuki, Suzuki, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2014
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206732/
https://www.ncbi.nlm.nih.gov/pubmed/25077758
http://dx.doi.org/10.1538/expanim.63.289

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