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Analysis of Statistical Methods Currently used in Toxicology Journals
Statistical methods are frequently used in toxicology, yet it is not clear whether the methods employed by the studies are used consistently and conducted based on sound statistical grounds. The purpose of this paper is to describe statistical methods used in top toxicology journals. More specifical...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society Of Toxicology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206745/ https://www.ncbi.nlm.nih.gov/pubmed/25343012 http://dx.doi.org/10.5487/TR.2014.30.3.185 |
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author | Na, Jihye Yang, Hyeri Bae, SeungJin Lim, Kyung-Min |
author_facet | Na, Jihye Yang, Hyeri Bae, SeungJin Lim, Kyung-Min |
author_sort | Na, Jihye |
collection | PubMed |
description | Statistical methods are frequently used in toxicology, yet it is not clear whether the methods employed by the studies are used consistently and conducted based on sound statistical grounds. The purpose of this paper is to describe statistical methods used in top toxicology journals. More specifically, we sampled 30 papers published in 2014 from Toxicology and Applied Pharmacology, Archives of Toxicology, and Toxicological Science and described methodologies used to provide descriptive and inferential statistics. One hundred thirteen endpoints were observed in those 30 papers, and most studies had sample size less than 10, with the median and the mode being 6 and 3 & 6, respectively. Mean (105/113, 93%) was dominantly used to measure central tendency, and standard error of the mean (64/113, 57%) and standard deviation (39/113, 34%) were used to measure dispersion, while few studies provide justifications regarding why the methods being selected. Inferential statistics were frequently conducted (93/113, 82%), with one-way ANOVA being most popular (52/93, 56%), yet few studies conducted either normality or equal variance test. These results suggest that more consistent and appropriate use of statistical method is necessary which may enhance the role of toxicology in public health. |
format | Online Article Text |
id | pubmed-4206745 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Korean Society Of Toxicology |
record_format | MEDLINE/PubMed |
spelling | pubmed-42067452014-10-23 Analysis of Statistical Methods Currently used in Toxicology Journals Na, Jihye Yang, Hyeri Bae, SeungJin Lim, Kyung-Min Toxicol Res Articles Statistical methods are frequently used in toxicology, yet it is not clear whether the methods employed by the studies are used consistently and conducted based on sound statistical grounds. The purpose of this paper is to describe statistical methods used in top toxicology journals. More specifically, we sampled 30 papers published in 2014 from Toxicology and Applied Pharmacology, Archives of Toxicology, and Toxicological Science and described methodologies used to provide descriptive and inferential statistics. One hundred thirteen endpoints were observed in those 30 papers, and most studies had sample size less than 10, with the median and the mode being 6 and 3 & 6, respectively. Mean (105/113, 93%) was dominantly used to measure central tendency, and standard error of the mean (64/113, 57%) and standard deviation (39/113, 34%) were used to measure dispersion, while few studies provide justifications regarding why the methods being selected. Inferential statistics were frequently conducted (93/113, 82%), with one-way ANOVA being most popular (52/93, 56%), yet few studies conducted either normality or equal variance test. These results suggest that more consistent and appropriate use of statistical method is necessary which may enhance the role of toxicology in public health. The Korean Society Of Toxicology 2014-09 /pmc/articles/PMC4206745/ /pubmed/25343012 http://dx.doi.org/10.5487/TR.2014.30.3.185 Text en Copyright © 2014, The Korean Society Of Toxicology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Na, Jihye Yang, Hyeri Bae, SeungJin Lim, Kyung-Min Analysis of Statistical Methods Currently used in Toxicology Journals |
title | Analysis of Statistical Methods Currently used in Toxicology Journals |
title_full | Analysis of Statistical Methods Currently used in Toxicology Journals |
title_fullStr | Analysis of Statistical Methods Currently used in Toxicology Journals |
title_full_unstemmed | Analysis of Statistical Methods Currently used in Toxicology Journals |
title_short | Analysis of Statistical Methods Currently used in Toxicology Journals |
title_sort | analysis of statistical methods currently used in toxicology journals |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206745/ https://www.ncbi.nlm.nih.gov/pubmed/25343012 http://dx.doi.org/10.5487/TR.2014.30.3.185 |
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