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Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression

BACKGROUND: Nodal signalling is an absolute requirement for normal mesoderm and endoderm formation in vertebrate embryos, yet the transcriptional networks acting directly downstream of Nodal and the extent to which they are conserved is largely unexplored, particularly in vivo. Eomesodermin also pla...

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Detalles Bibliográficos
Autores principales:	Nelson, Andrew C, Cutty, Stephen J, Niini, Marie, Stemple, Derek L, Flicek, Paul, Houart, Corinne, Bruce, Ashley EE, Wardle, Fiona C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206766/ https://www.ncbi.nlm.nih.gov/pubmed/25277163 http://dx.doi.org/10.1186/s12915-014-0081-5

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